Among open clinical protocols for solid tumors, CARs targeting mesothelin, which is overexpressed in a wide range of solid tumors [47], human epidermal growth factor receptor family members (HER2/ERBB2 and HER1/EGFR) overexpressed in breast, ovarian, bladder, salivary gland, endometrial, pancreatic, and non-small-cell lung cancer (NSCLC) [48–51], and neuroblastoma associated GD2 [52] antigens dominate. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.