On the venous side, recent evidences showed that the gene polymorphisms prothrombin (factor II) G20210A and factor V Leiden not only increase the already well-known risk for venous thromboembolism (VTE) deep vein thrombosis (DVT) and pulmonary embolism (PE) but also raise the risk for cerebral venous thrombosis, a stroke subtype that is particularly more common in women, especially of reproductive age [10, 20]. Here, F2 is linked to deep vein thrombosis.