AKT1 and cancer: Among these, miRNAs decreased with target genes increased in Sca-1+CD31− cells compared to Sca-1+CD31+ cells and were involved in cancer, PI3K-Akt signaling, Rap1 signaling, mTOR signaling, protein digestion and absorption, complement and coagulation cascade, cytokine-cytokine receptor interaction, and cancer pathways (Figure 7(a)).