High expression of MUC5AC was significantly associated with PFS (HR 0.13, 95 % CI 0.02–0.91, p = 0.04), while no association of MMR deficiency with PFS was observed (HR 1.06, 95 % CI 0.35–3.37, p = 0.92). The gene discussed is MUC5AC; the disease is hyperinsulinemic hypoglycemia, familial, 4.