SOX2 and Alzheimer disease: Interestingly, when we analyzed the proportion of cells co-expressing SOX2 and NeuN, we found that these were significantly more abundant in NDAN DG as compared to both MCI and AD subjects, whereas, on the other hand, cells that exclusively express SOX2 (NeuN−) were significantly more abundant in both NDAN and MCI DG as compared to AD and healthy controls.