While the induction of CXCR2 and ligands by Kras has been shown to reinforce senescence in vitro and is thought to be protective in the early stages of tumorigenesis 27, CXCR2 ligands have been implicated in the angiogenesis and proliferation of tumours and in neutrophil recruitment to the tumour 7, 8. Here, CXCR2 is linked to neoplasm.