The main inflammatory cytokines, for example, tumour necrosis factor‐alpha (TNF‐α), interleukin‐6 (IL‐6) and IL‐8; chemokines such as chemokine (C‐X‐C Motif) Ligand 12 (CXCL12); and growth factors, for instance, vascular endothelial growth factor (VEGF), are crucial factors present in the inflammatory tumour microenvironment 6. This evidence concerns the gene TNF and neoplasm.