The relative risks of aCL positive outpatient dogs (vs. aCL negative outpatient dogs) for having thrombocytopenia (Group I), immune thrombocytopenia with aPLT (subgroup IA), severe thrombocytopenia without aPLT (IB), and less severe thrombocytopenia (IC) were 8.3, 5.3, ∞ (odds ratio 19) and ∞ (odds ratio 27), respectively. This evidence concerns the gene ACLY and autoimmune thrombocytopenic purpura.