TARDBP and Alzheimer disease: Marquie et al [19], present that AV-1451 does not bind to non-AD tauopathies or TDP-43 but Sanders, et al, have data that suggest that AV-1451 does bind to non-AD tauopathies (greatest in PiD and FTDP-17) and additionally to FTLD-TDP Types A and C (1/3 cases for each type).