The ASS HCC related biomarkers (Table 3A) were mainly: metabolic enzymes (PDE5A, ALDOA, ACAA1, SERPINA1), heat shock protein (HSPA4), cadherin (CDH1), keratin (KRT1), nucleosome assembly protein (NAP1L4) and glycoprotein (ORM1). The gene discussed is NAP1L4; the disease is hepatocellular carcinoma.