Although such cases may share the basic lesion, i.e. chondrodysplasia, during examination in the field, significant variation in the phenotype may be found during post mortem examination, e.g. the syndrome reported by Berger and Innes [19] had severe hydrocephalus, which distinguishes it from the COL2A1 associated “Igale Masc” and “VH Cadiz Captivo” types. The gene discussed is COL2A1; the disease is chondrodysplasia.