Because the kinetics of teratoma formation is dependent on the number of remaining pluripotent stem cells during the differentiation procedure [93-98], it might be tempting to suggest that loss of PINK1-driven mitophagy facilitates the depletion of residual undifferentiated pluripotent cells (teratocarcinoma-initiating cells) during in vivo teratoma formation. The gene discussed is PINK1; the disease is teratocarcinoma.