TP53 and metastasis: However, LSR did not show any significant association with age (p = 0.148), smoking behavior (p = 0.141), family history (p = 0.515), TNM stage (p = 0.425), lymph node metastasis (p = 0.168), distant metastases (p = 0.294), tumor location (p = 0.247), serous infiltration (p = 0.055), CA72-4 (p = 0.600), CEA (p = 0.793), Fbg (p = 0.694), GPS (p = 0.054), p53 (p = 0.075), and blood type (p = 0.736).