IGHE and asthma: Using skin prick dust mite sensitization, food allergen sensitization, personal history of allergic rhinitis, personal history of asthma, and the NESS, logistic regression showed that hyper-IgE was associated with a personal history of asthma (exp(B) = 5.12, p = 0.002) and eczema severity during childhood and adolescence (p < 0.001).