Tumor size (OR, 2.391; 95% CI, 1.057–5.407; P=0.036), differentiation (OR, 2.936; 95% CI, 1.033–8.343; P=0.043), intravascular tumor thrombi (OR, 3.826; 95% CI, 1.094–13.385; P=0.036) and OLFM4 expression (OR, 4.193; 95% CI, 1.859–9.458; P=0.001) were identified as independent predictive factors for LNM in EGC patients after adjustment of covariates (Table 3). Here, OLFM4 is linked to neoplasm.