Urinary KIM-1 levels have also been found to be correlated with the urinary IL-18 and angiotensinogen, body mass index, duration of diabetes, glycemic control, and systolic and diastolic blood pressures (BP), which may reflect the role of Kim-1 as a marker for diagnosis and prognosis of DN among diabetic patients taking into account other risk factors [19, 21, 39–41]. This evidence concerns the gene IL18 and diabetes mellitus.