Blood pressure in MS rats is higher than in control animals at 6 months of age and then decreases; this might be a selection of those rats with the capacity to compensate for the hypertensive state showing chronic compensatory changes in signaling molecules such as the increase in seric Ang 1-7 concentration that may restore blood pressure and a decrease in the concentration of Ang II (Table 2). Here, AGT is linked to myeloid sarcoma.