Many of the early typical abnormalities targeted and observed here included severe hypoinsulinemia (Figure 5), hyperglycemia (Figure 1), body weight loss (Figure 2), water intake (Figure 3(b)), urine output (Figure 3(a)), serum albumin decline (Figure 8(a)) with albuminuria (Figure 8(b)), and elevation in serum and urine creatinine concentration and creatinine clearance (Figure 9), in addition to moderate hypertension (Figure 4). The gene discussed is ALB; the disease is Hypertension.