reported that an elevated preoperative level of soluble PD‐L1 is associated with an increased risk of death from ccRCC, and they suggested that release of soluble PD‐L1 molecules may be a mechanism by which tumors impair systemic antitumor immunity, suggesting that inactivation or removal of soluble PD‐L1 from the serum could be clinically beneficia 26. Here, CD274 is linked to nonpapillary renal cell carcinoma.