DNER and triple-negative breast carcinoma: The bromodomain and extra-terminal (BET) proteins are lysine acetylation readers that mediate gene expression, including oncogenes.1 BET inhibitors (BETi) demonstrate many anticancer effects by downregulating gene expression of oncogenic factors.2 Breast cancer is the most common female cancer and triple negative breast cancer (TNBC) is its most aggressive subtype.