Genome-wide methylation analysis that was carried out using Infinium HumanMethylation450K BeadChip array, revealed Cbx7 as one of the hypermethylated genes in GBM (Fig. 1A) and lower grades of glioma (Fig. 1B) compared to control brain samples in our cohort, GSE 228867 and TCGA data sets. Here, CBX7 is linked to glioma.