VDAC1 and cancer: Several studies have shown differences in the expression of VDAC between cancer cell lines and tissues with respect to the normal counterparts: high VDAC1 levels were observed in hepatoma, sarcomatous alterations (Yoo et al. 2009), non-small-cell lung cancer (NSCLC) cells (Brahimi-Horn et al. 2012), gastric cancer cells (Bai et al. 2011) and different cancer types, such as thyroid, lung, cervix, ovary, pancreas, melanoma and glioblastoma cancers.