ARX and epilepsy: Our previous findings are consistent with this hypothesis; the epilepsy phenotype was observed in mice in which Arx was conditionally abrogated from interneurons (the Arx−/Y; Dlx5/6cre-IRES-GFP(CIG) cross) but not when Arx is selectively excised from dorsal progenitors of projection neurons (Arx−/Y; EmxCRE cross) [2, 12].