In lung cancer characterized with PD-L1 expression, expression rates varied from 24 to 60 % using the same 5 % cut-off value [15, 16, 42], and from 21 to 95 % according to different cut-off values of 1, 10 and 50 % [13, 17, 18, 43]. This evidence concerns the gene CD274 and lung carcinoma.