The matricellular protein Cyr61, which in vivo is highly relevant for the induction of angiogenesis [19], one of the key factors for tumor growth and metastasis [20], binds to proteins in the extracellular matrix [21, 22] and is shown here being expressed in the TNBC cell lines MDA-MB-231 and BT549. This evidence concerns the gene CCN1 and neoplasm.