Other groups have reported an inhibition of the mTOR pathway and activation of AMPK by quercetin at concentrations ≥ 25μM in prostate, colon, and other BC cell lines [44], Our studies show inhibition of Akt/mTOR activities by quercetin treatment at a lower concentration (15μM) that is closer to the physiological levels achieved after ingestion of a quercetin supplement. Here, AKT1 is linked to breast cancer.