An analysis of transwell invasion (Figure 2B) and transendothelial migration (Figure 2C) indicated that expressions of these genes were not correlated with the properties of migration and invasiveness of each pancreatic cancer cell, suggesting that each pancreatic cancer cell has LOXL2- independent mechanisms to control the expression of LOXL2, Snail, CDH1, and L1CAM, which is related to EMT and invasiveness. The gene discussed is CDH1; the disease is familial pancreatic carcinoma.