NSD3 and head and neck squamous cell carcinoma: To assess whether WHSC1L1 induces H3K36 dimethylation in SCCHN cells, we performed knockdown experiments of WHSC1L1 in YD-10B and HN13 SCCHN cells using two WHSC1L1 specific siRNAs (siWHSC1L1#1 and siWHSC1L1#2).