Multiple TNBC subtypes have been described, among which is basal-like subtype(BL1 and BL2) that harbors mutation of the breast cancer-associated gene 1(BRCA1), which was discovered as the first breast cancer susceptibility gene in familial breast cancer [10], and is defective in DNA repair [11], and the luminal androgen receptor subtype (LAR) which expresses AR. The gene discussed is BRCA1; the disease is hereditary breast carcinoma.