ESR1 and breast cancer: The following interpretations were newly added to the conclusion of Zhang et al. [5]: (1) AC and CX have a protective effect against all breast cancers regardless of ER/PR status; (2) all five types of carotenoids are effective in suppressing ER− breast cancer; (3) BC increases the risk of developing ER+ or ER+/PR+ breast cancer; (4) along with AC, BC, and LY, LZ also suppresses ER−/PR+ breast cancer; and (5) AC, LZ, and LY, along with BC, suppress ER−/PR− breast cancer.