We observed that the association was far stronger for IDH-mutant gliomas compared to IDH-wt gliomas (ORs of 9.25 vs. 2.49; p < 0.0001 vs. p = 0.033; n = 153 vs. 116, respectively) (Fig. 2a and Supplementary Table 2). The gene discussed is IDH2; the disease is central nervous system cancer.