NGFR and central nervous system cancer: In addition to the xenograft model generated by human lung non-small cell carcinoma H460 cells (Figure 8), NGFR has also been shown by others to enhance cell survival of schwannoma (Ahmad et al., 2014; Gentry et al., 2000), melanoma (Boiko et al., 2010), and breast cancer (Descamps et al., 2001), and to promote metastasis of glioma (Johnston et al., 2007), melanoma (Boiko et al., 2010), and head and neck cancers (Murillo-Sauca et al., 2014) (Figure 8H).