CTNNB1 and breast cancer: In contrast, both collective changes in the percentage (37% in PAM50 Basal-like subtype of IDC and 40% in triple negative breast tumors) as well as the percentage of alterations of individual genes of CTNNB1 (15% in PAM50 Basal-like subtype of IDC and 18% in triple negative breast tumors), APC (9% for both) and DVL1 (13% for both) were found significantly higher in both PAM50 Basal-like subtype of IDC and triple negative breast tumors as compared to other subtypes of BC (Figure 1B).