SLC10A2 and diabetes mellitus: The similar results were obtained in the following studies both in vitro and in vivo: (i) in vitro exposure to glucose increased the mature glycosylated ASBT protein, but not the core glycosylated ASBT, probably via promoting its stability [25]; (ii) in diabetes model rat, mature glycosylation form of native UT-A1, an urea transporter showing apical localization in polarized cells, was increased with the change in its glycosylation profile [48].