The T2D risk alleles of genetic variants in BCL11A, PPARG, CDKAL1, CDKN2BAS, CHCHD9, CDC123/CAMK1D, MTNR1B, and KCNQ1 were related to a decreased measurement of at least one of the obesity-related traits (body weight, BMI, WC, WHR), whereas the T2D risk alleles of genetic variants of WFS1, TP53INP1, and FTO were associated with a higher measurement. The gene discussed is WFS1; the disease is Obesity.