TNFRSF4 and neoplasm: This result agrees with prior studies demonstrating that anti-OX40 must be present during the key period, 12–24 hours following antigen exposure to coincide with OX40 upregulation on T cells [17], and with the evidence that tumor antigen-presentation approximately 2 days following radiation therapy [3], suggesting that 5 days post-radiation therapy will be beyond this therapeutic window.