LAMC2 and familial pancreatic carcinoma: LAMC2 (a major component of laminin-5) has been reported to be highly expressed in several types of invasive tumors [35, 36] including carcinomas of the pancreas [37, 38], tongue [39, 40], colorectal [41, 42], lung [43], cervix [44], lung [45], extra hepatic cholangiocarcinoma.