AKT1 and juvenile Huntington disease: ‘Purine metabolism’ pathway had the largest number of unigenes (166), followed by ‘Lysosome’ (164 unigenes), ‘HTLV-I infection’ (159 unigenes), ‘Spliceosome’ (156 unigenes), ‘Huntington's disease’ (155 unigenes) and ‘PI3K-Akt signaling pathway’ (147 unigenes) (Fig 6).