A list of 20 genes was compiled, for which protein expression was associated with EGFR TKI response in patient-derived lung cancer xenografts, or mutations have been observed in these models14: In more detail, the proteins coding for mTOR, PRKAA1, RAF1, RPS6KA1, and RPS6KAB1 were differentially expressed in RPPA analysis of NSCLC xenograft models14. The gene discussed is PRKAA1; the disease is non-small cell lung carcinoma.