A list of 20 genes was compiled, for which protein expression was associated with EGFR TKI response in patient-derived lung cancer xenografts, or mutations have been observed in these models14: In more detail, the proteins coding for mTOR, PRKAA1, RAF1, RPS6KA1, and RPS6KAB1 were differentially expressed in RPPA analysis of NSCLC xenograft models14. This evidence concerns the gene RAF1 and lung carcinoma.