This study intend to compare the plasma concentrations of S100B between patients with schizophrenia and healthy volunteers, and to explore if the levels of inflammatory markers (including hsCRP, IL-17), regulation factors (including transforming growth factor-beta 1, IL-23, IL-10) and complement factor 3, are associated with plasma levels of S100B in patients with schizophrenia. This evidence concerns the gene S100B and schizophrenia.