Similar to U1-70K, a number of the other autoantibody associations we observed paralleled previous studies on IFN gene scores in SLE, including dsDNA4, 20, 22, 23, 25, Smith19, 20, 22, Ribo P19, and specific histone proteins (H1, H2A, H2B, and H3/H4)24, further confirming their association with dysregulated IFN signaling. Here, IFNA1 is linked to systemic lupus erythematosus.