KLF4 and adenocarcinoma: In consistent with the TMA results, KLF4 was downregulated in all subtypes of stomach adenocarcinoma, while MUC2 was found to be induced in mucinous type of stomach intestinal adenocarcinoma (Figure 6), further indicating the effect of KLF4 deletion in inducing MUC2 expression and in facilitating formation of this particular type of adenocarcinoma.