This was unexpected since microtubule alterations in mutant SOD1-linked ALS have so far been only reported in axons, as illustrated by a reduction in axonal tubulin transport [70], an accumulation of βIII-tubulin in axonal swellings [70] and increases in hyperdynamic microtubules [17] or density of EB3 comets [27] in axons. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.