In contrast to all other groups, but similarly to the MMP-9 patterns, the patients with hepatic breast cancer metastases demonstrated also well consolidated MMP-2 profiles reflecting the same main feature, namely an increasing and stably high level of MMP-2 activity after the SIRT application that corresponds to the patterns 2A1, 2B, 3A, 3B1. The gene discussed is MMP2; the disease is breast carcinoma.