MGMT and neoplasm: We also studied a number of visual/qualitative measures [enhancing tumor margin (well or poorly defined); enhancement pattern (ring, nodular, or mixed enhancement); presence of edema, cystic regions, necrosis, and nonenhancing tumor; and heterogeneity of the signal intensity on the T2-weighted images], but none was correlated with MGMT methylation status, which is in agreement with previous results.11,12