KRT18 and hepatocellular carcinoma: Concerning the result of serum AFP there was significant increase in its levels in GII in comparison to GI, control group with sensitivity and specificity 45% and 96.6%, respectively (3 patients in G2 with hepatic focal lesions, AFP was below diagnostic level for HCC so liver biopsy and histo-pathological examination was done) while serum CK18 was highly significantly increased in GII in com-parison to GI and control group with sensitivity and specificity of 95% and 96.7% (Fig. 1, 2), (Table 4).