MVP and pulmonary arterial hypertension: Fig. 1 shows that MVP is expressed in the left ventricle (LV) and the right ventricle (RV) of the heart in normal rats as well as in the hypertrophied RV in rats with pulmonary arterial hypertension (PAH). Immunohistochemistry also shows the expression of MVP in cardiac muscle as well as in coronary artery smooth muscle in normal rats (Fig. 2B).