STAT3 and colorectal carcinoma: Moreover, the western blot analysis (Figure 1(c)) indicated that both markers in protein levels were also significantly higher in the CRC tissues (n = 15) than in the paratumor tissues (p < 0.01) (n = 15) (p < 0.01 for Anxa 2 and p < 0.05 for STAT3, Figure 1(d)).