In fact, ZIP–2 target genes which include the cohort of detoxification genes (CYP–14A5, pgp–5, pgp–7, ugt–31 and ugt–29) and infection response genes (irg–1 and irg–2) were amongst the most robustly induced transcriptional suite in response to B. pseudomallei infection4. The gene discussed is IFIT3; the disease is infection.