EIF4E and neoplasm: There are a subset of mRNAs encoding proliferation, survival and tumour-promoting proteins including cyclins32, ornathinine decarboxylase (ODC)33, VEGF34, MYC35 and phosphoribosyl-pyrophosphate synthetase2 (PRPS2)36, which are referred to as eIF4E-sensitive mRNAs21.