The lung tumorigenesis data showed that at 1.5 years after whole-body exposure to 1 Gy of IR (X-ray), lung adenocarcinoma genesis in Gprc5a−/− mice increased from 10 to 35% (Fig. 4d); whereas, wild-type mice only showed 1.3% lung adenocarcinoma30. This evidence concerns the gene GPRC5A and lung adenocarcinoma.