Furthermore, renal levels of S100a8/a9 mRNAs for calprotectin, a heterodimeric protein that was recently found to co-localize with Ly6G in granulocytes after AKI and playing a crucial part in controlling M2 macrophage-mediated renal repair following IRI23, were also not significantly different (Supplementary Figure 3C,D). This evidence concerns the gene S100A8 and acute kidney injury.